Several factors influence neoprene modified asphalt waterproofing in bitumen modification systems. Key factors include the quality and compatibility of neoprene with the asphalt matrix, the concentration of neoprene used, and the processing conditions during mixing. Additionally, environmental factors such as temperature and humidity during application, as well as the substrate’s surface preparation, play crucial roles in achieving optimal adhesion and waterproofing performance. Proper curing time and conditions also significantly affect the final properties of the modified asphalt.